GLP1s are a medication that works by mimicking the effects of a hormone called glucagon-like peptide-1 , which helps to regulate insulin levels, reduce appetite, and increase feelings of fullness. Clinical trials have shown these medications can lead to significant weight loss in individuals struggling with obesity.

2. GIP/GLP-1 receptor agonist demonstrated effectiveness in reducing body weight and improving metabolic health in clinical studies.

-Who should not take GLP1 or GIP/GLP1 medications: Individuals who are pregnant or may become pregnant, breastfeeding, history of pancreatitis, multiple endocrine neoplasia, or medullary thyroid carcinoma.

Pricing includes the cost of the medication, shipping, supplies, administration services and medical management fees.

GLP1 with or without glycine and B12

Starter Pack: $459 for 10 week supply

Continued dosing:

$489 for <1mg dosing for 10-12 week supply

$549 >1mg dosing for 8-12 weeks supply depending on dose

Monthly dosing- $279 for 4 weeks of medciation at any dose with B12

GLP1 /GIP with or without glycine and B12

Starter Pack:

$579 for a 10 week supply

Continued Dosing:

$699 and week supply varies on dose

Monthly Dosing with B12:

7 mg or less $339

>7 mg dosing: $449

Cash Pay options for name brand medications will be the 5 week management fee which is $140 and then pharmacy will reach out to the patient directly for payment

Contraindications

Glycine contraindicated in:

• Kidney/liver disease

• Seizure or Parkinson’s history

• Severe hypotension or uncontrolled diabetes

B12 contraindicated in:

• Kidney disease

• Leber’s hereditary optic neuropathy

GLP1/GIP contraindications with Premier HealthCO and will result in denial:

• MTC or MEN2, thyroid cancer

• CKD stage IIIb or worse

• Gallbladder disease, pancreatitis history, gastroparesis

• Bariatric surgery <12 months

• Pregnancy/ breastfeeding

• Albumin/protein abnormalities, AST/ALT >2.5x ULN

• Triglycerides ≥980 mg/dL

• Cardiac event in past 6 months

• Age >64

• Use of insulin/sulfonylureas or interacting drugs (warfarin, lithium, anti-arrhythmics)

• provider discretion

• BMI not meeting prescribing guideines

• falsified medical history provider to provider

MIC + B12 Injection

Price: $189 for 5-10 week supply depending on dose

A targeted injection to support fat metabolism, liver health, and energy production.

MIC + B12 is a specially formulated intramuscular injection that combines Methionine, Inositol, and Choline (MIC) with Vitamin B12. This synergistic blend is designed to support fat metabolism, enhance energy levels, and aid in liver function—key components in many medical weight loss and wellness programs.

These injections are often used as part of a broader health protocol to assist individuals in achieving their wellness goals, particularly when combined with provider-led dietary and lifestyle interventions.

⚡ Potential Benefits May Include:

• Enhanced Fat Metabolism: MIC compounds help break down fat in the liver, supporting fat-burning processes when paired with proper nutrition and exercise.

• Increased Energy & Focus: B12 supports red blood cell production and nervous system function, helping reduce fatigue and boost mental clarity.

• Liver Support: Choline plays a key role in liver detoxification and bile production, promoting healthy organ function.

• Metabolic Support: May assist in supporting healthy metabolic rate and cellular energy.

Who Should Not Use MIC + B12:

MIC + B12 injections may not be suitable for everyone. This treatment is not recommended for individuals who:

• Have a known allergy to any of the ingredients, including Methionine, Inositol, Choline, or Vitamin B12

• Have Leber’s disease (a rare hereditary eye condition), as B12 may increase risk of optic nerve damage

• Have chronic liver or kidney disease, unless cleared by a provider

• Are pregnant or breastfeeding without prior approval from a medical provider

• Are taking medications that may interact with B12 or MIC compounds (e.g., chloramphenicol, certain chemotherapy agents, or metformin)

• Have certain electrolyte imbalances or endocrine disorders that require more advanced medical oversight

A full medical consultation is required prior to treatment. Your provider will assess your medical history, symptoms, and any medication use to determine if MIC + B12 is appropriate for your care plan.

Methyl B12 Injection

Pricing: $189 for 5 week supply

A bioavailable form of Vitamin B12 designed to support energy, mood, and neurological health.

Methyl B12 (methylcobalamin) is a naturally occurring, active form of Vitamin B12 that plays a vital role in nervous system function, energy production, and mood regulation. Unlike synthetic forms of B12 (like cyanocobalamin), methylcobalamin is readily absorbed and utilized by the body, making it a preferred choice for patients with B12 deficiencies or those seeking enhanced cognitive and metabolic support.

This intramuscular injection delivers rapid and efficient absorption, helping to support cellular function and overall vitality.

⚡ Potential Benefits May Include:

• Increased Energy Production: Supports red blood cell formation and cellular energy metabolism, helping reduce fatigue and improve stamina.

• Neurological Support: May assist in protecting nerve cells and reducing symptoms related to B12 deficiency.

• Mood & Cognitive Function: Supports neurotransmitter activity, helping promote mental clarity and balanced mood.

• Improved Sleep Quality: Some individuals report improved sleep patterns with B12 support.

🚫 Who Should Not Use Methyl B12:

Methyl B12 injections are not appropriate for everyone. You should not receive this treatment if you:

• Have an allergy to cobalt or Vitamin B12

• Have Leber’s disease (a hereditary eye condition) — use of B12 may lead to optic nerve damage

• Have a history of megaloblastic anemia due to folate deficiency (without concurrent folate therapy)

• Are currently pregnant or breastfeeding without clearance from a medical provider

• Have certain kidney disorders, especially if receiving high-dose supplements

• Are currently taking certain medications such as chloramphenicol (antibiotic) or metformin (which may alter B12 absorption—requires provider review)

A full medical evaluation is required prior to beginning treatment to assess individual risk factors and ensure this therapy is appropriate for you.

Tesamorelin Peptide Therapy

$329 for a 5 weeks supply

A prescription peptide that supports fat metabolism, body composition, and natural growth hormone stimulation.

Tesamorelin is a synthetic peptide analog of growth hormone–releasing hormone (GHRH), designed to stimulate the body’s natural production of human growth hormone (HGH). Originally FDA-approved for the reduction of visceral abdominal fat in HIV-associated lipodystrophy, Tesamorelin is now increasingly used off-label to support metabolic function, fat loss, and age-related hormone decline under medical supervision.

At Premier HealthCO, Tesamorelin may be incorporated into a personalized protocol aimed at improving body composition, recovery, and overall metabolic wellness, when deemed appropriate by a licensed provider.

⚡ Potential Benefits May Include:

• Reduction in Visceral Fat: Tesamorelin has been shown to reduce deep abdominal fat, especially when combined with a healthy lifestyle.

• Improved Body Composition: May help promote lean muscle mass and support fat loss.

• Hormone Optimization: Stimulates endogenous growth hormone, which can benefit metabolism, skin, sleep, and recovery.

• Cognitive & Cardiovascular Support: Preliminary studies suggest potential support for brain and heart health, though not FDA-approved for these uses.

🚫 Who Should Not Use Tesamorelin:

Tesamorelin is not appropriate for everyone. You should not use this peptide if you:

• Have an active malignancy (cancer), or a history of cancer that is not under medical clearance

• Are pregnant or breastfeeding

• Have untreated pituitary tumors, diabetes, or active diabetic retinopathy

• Have a known allergy to Tesamorelin or its components

• Have a medical condition where increased growth hormone levels may be harmful

• Are using other medications that may interfere with growth hormone pathways (provider will evaluate)

A comprehensive medical consultation and lab review are required before initiating treatment. All prescribing decisions are made solely by a licensed provider based on your health history, goals, and lab results.

📌 Important Notice:

Tesamorelin is a prescription-only peptide and should only be used under the supervision of a licensed healthcare provider. While Tesamorelin is FDA-approved for a specific indication (HIV-associated lipodystrophy), all other uses are considered off-label. This information is provided for educational purposes only and does not replace medical advice.

AOD-9604 Peptide Therapy

AOD9604 $329 for 5 week supply

AOD/combo $359 for 5 week supply

A targeted peptide developed to support fat metabolism and body composition.

AOD-9604 is a lab-engineered peptide fragment derived from the human growth hormone (HGH) molecule. Specifically designed to stimulate lipolysis (fat breakdown) without the full effects of HGH, AOD-9604 is commonly used off-label to support body fat reduction, metabolic wellness, and weight management goals under medical supervision.

While originally researched for obesity-related treatment, AOD-9604, research suggets it does not impact growth hormone levels and has shown promise in helping reduce body fat when combined with proper diet, activity, and lifestyle changes.

⚡ Potential Benefits May Include:

• Targeted Fat Reduction: May help reduce stubborn body fat, especially in the abdominal region.

• Metabolic Support: Promotes lipolysis (fat breakdown) and inhibits lipogenesis (fat formation).

• Joint & Cartilage Support: Some users report decreased joint discomfort and improved mobility.

• Weight Loss Assistance: May support overall body composition goals when combined with a medical weight loss program.

➕ AOD-9604 + MOTs-c (Combination Therapy)

When used with MOTs-c—a mitochondrial-derived peptide that supports metabolic regulation, glucose control, and cellular energy—this protocol may further enhance:

• Fat-burning efficiency

• Insulin sensitivity

• Energy metabolism and endurance

• Mitochondrial function for cellular health

This pairing is often selected for patients with metabolic resistance, fatigue, or weight plateaus.

➕ AOD-9604 + MOTs-C+ Tesamorelin (Combination Therapy)

Combining AOD-9604 with Tesamorelin may offer synergistic effects in reducing visceral fat while preserving or enhancing lean body mass.
Tesamorelin supports the body's natural growth hormone production, while AOD-9604 focuses on fat breakdown—making this stack appropriate for provider-supervised body composition protocols.

🚫 Who Should Not Use AOD-9604 (or Combinations):

These peptides may not be appropriate for individuals who:

• Are pregnant or breastfeeding

• Have an active cancer diagnosis or history of hormone-sensitive cancers

• Have diabetes or uncontrolled blood sugar disorders (without clearance)

• Have a known allergy to any peptide or formulation components

• Are on medications that may interact with mitochondrial or hormone pathways

• Have severe kidney, liver, or cardiac conditions

All peptides should only be prescribed after a comprehensive evaluation by a licensed healthcare provider. Combined peptide protocols require further assessment to ensure safety and appropriateness for your specific health profile.

📌 Important Notice:

AOD-9604 and any combinations with MOTs-c or Tesamorelin are considered off-label therapies and are not FDA-approved for weight loss or metabolic conditions. This information is provided for educational purposes only and does not replace medical advice. These peptides are available by prescription only, and should only be used under medical supervision after a provider determines clinical appropriateness.